Gated SPECT: What’s the ideal method to measure LVEF?

Overestimation of the LVEF by quantitative gated SPECT in simulated left ventricles.

UNLABELLED During routine myocardial perfusion imaging, a common observation is that patients with normal cardiac function and small hearts, in particular small women, have higher left ventricular ejection fractions (LVEFs), as measured by quantitative gated SPECT (QGS) software, than anticipated, often markedly so. The goal of this project was to determine if the QGS LVEF varies with the chang...

Quantitative LVEF and qualitative regional function from gated thallium-201 perfusion SPECT.

UNLABELLED This study investigates the feasibility of routine clinical 201Tl gated perfusion SPECT (gated Tl), and compares quantitative left ventricular ejection fraction (LVEF) and visually-assessed regional wall motion and thickening to analogous values obtained from 99mTc-sestamibi gated perfusion SPECT (gated MIBI). METHODS We studied 121 patients with a rest gated Tl (3-3.5 mCi, 35 sec/...

The role of SPECT and gated SPECT

Combination of physical exercise and adenosine improves accuracy of automatic calculation of stress LVEF in gated SPECT using QGS software.

BACKGROUND Combining exercise and adenosine during the stress phase of myocardial perfusion imaging (MPI) is known to reduce adverse effects and improve image quality. The aim of this study was to assess whether it can also improve the automatic calculation of left ventricular ejection fraction (LVEF) by QGS software package, during the stress phase of Gated SPECT. MATERIAL AND METHODS One hu...

The role of oral dipyridamole stress gated SPECT in assessing the response of the left ventricle to stress: Re-evaluation of an old method

Introduction: We aimed to assess whether the vasodilator effect of oral dipyridamole on the left ventricular systolic function in patients with suspected CAD is different from that of intravenous (IV) dipyridamole using Tc-99m MIBI myocardial perfusion gated SPECT. Methods: Eighty-nine patients (17 M / 72 W; 61 ± 10 years) were enrolled in this study. The patients underwent a dipyridamole stre...